Pneumonia em organização secundária ao uso do everolimus – relato de caso
نویسندگان
چکیده
Objetivo: Relatar o caso de uma paciente que desenvolveu pneumonia em organização (PO) com presumida associação ao uso do everolimus. Metodologia: Estudo tipo relato caso, tendo os dados sido coletados por meio prontuário médico e a revisão bibliográfica pesquisada pelo PUBMED. Resultados: O é 66 anos realizou transplante renal, após, iniciou tacrolimus Depois 1 ano cinco meses tosse seca febre. Então internou-se para investigação, sendo excluídas causas infecciosas autoimunes. Progrediu piora clínica, foi entubada permaneceu leito terapia intensiva. Foi realizado biópsia pulmonar resultado compatível PO. quadro clínico correlacionado everolimus, suspenso iniciado prednisona, evoluindo melhora clínica. Conclusão: Os inibidores da mTOR são medicações forte desenvolvimento doenças pulmonares intersticiais. A temporalidade, na literatura, variável desde início everolimus surgimento dos primeiros sintomas. Nesse droga relacionada PO, maior número casos literatura quando comparado tacrolimus, cujas evidências mais fracas.
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ژورنال
عنوان ژورنال: Revista de Medicina da Universidade Federal do Ceará
سال: 2023
ISSN: ['2447-6595', '0100-1302']
DOI: https://doi.org/10.20513/2447-6595.2023v63n1e78229p1-5